2023 Fiscal Year Final Research Report
Does physical activity predict the incidence of morphometric vertebral fracture in community-dwelling elderly Japanese men ? : Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Cohort Study
| Project/Area Number |
19K11674
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 59040:Nutrition science and health science-related
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| Research Institution | Kitasato University |
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Principal Investigator |
Kitagawa Jun 北里大学, 一般教育部, 教授 (80260529)
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| Co-Investigator(Kenkyū-buntansha) |
伊木 雅之 近畿大学, 医学部, 教授 (50184388)
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| Project Period (FY) |
2019-04-01 – 2024-03-31
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| Keywords | 男性 / 身体活動 / 身体機能 / 新規椎体骨折 / コホート研究 |
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| Outline of Final Research Achievements |
This study aimed to determine whether physical activity can predict the subsequent incidence of morphometric vertebral fracture (MVF) in elderly men after adjusting for confounding factors. A total of 1350 Japanese men aged over 65 years completed the baseline study, including measurement of daily physical activity using the International Physical Activity Questionnaire and physical performance tests (walking speed, hand grip strength, and one-leg standing) in 2007 and 2008. Participants were then invited to attend follow-up study visits five and ten years later to identify incident of MVF. Multivariable logistic regression was used to determine the association between physical activity and incidence of MVF as the outcome.
We identified 47 MVFs in 1350 men during follow-up period. After adjusting for potential confounding factors, daily physical activity at baseline was not associated with risk of MVF, whereas higher grip strength was associated with a lower risk of MVF
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| Free Research Field |
健康科学
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| Academic Significance and Societal Importance of the Research Achievements |
椎体（背骨の骨）骨折は大腿骨近位部（付け根）骨折のようにすぐにはADL（日常生活動作）やQOL（生活の質）の低下，死亡リスクの上昇に結びつくわけではないが，中長期的には確実にこれら健康指標の増悪（負の連鎖）をもたらすため，形態骨折発生の予測因子を見いだし，予防策を講じることは健康寿命（自立して健康に暮らせる期間)延伸に寄与しうる。超高齢化社会の日本において健康寿命を延伸するためには，運動習慣を持ち，筋力を維持することの重要性を示すことができたことは大きな成果である。
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