Clinical application of skin color measured by spectrophotometer: Relationship between skin color and pathophysiology in perisurgical patients.

2022 Fiscal Year Final Research Report

• Project/Area Number: 19K12914
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 90150:Medical assistive technology-related
• Research Institution: Tokai University
• Principal Investigator: Kutsuzawa Tomoko 東海大学, 医学部, 特任教授 (10183310)
• Co-Investigator(Kenkyū-buntansha): 秋月 有紀 富山大学, 学術研究部教育学系, 教授 (00378928)
• Project Period (FY): 2019-04-01 – 2023-03-31
• Keywords: 皮膚色 / 分光測色計 / 経カテーテル大動脈弁置換術 / 周術期 / ショック / 明度

Outline of Final Research Achievements

Time course changes in skin color was measured using spectrophotometry in case of perioperative period of transcatheter aortic valve implantation (TAVI) and patients with shock state. Skin lightness L* values increased 6 and 18 h after TAVI (early postoperative period), and skin color darkened at 72 h after TAVI (recovered condition). Patients with shock state occasionally showed decrease in skin lightness L* and increase in redness (a*) along with improvement of illness. The finding suggests that the objective measurement of skin color is useful to detect pathophysiological changes during acute phase of disease. Skin lightness was associated with hemoglobin or blood pressure in several, but no all, measured timepoints. Thus, multiple factors may relate to the changes in skin color during the acute state of disease.

Free Research Field

呼吸器内科学

Academic Significance and Societal Importance of the Research Achievements

皮膚色は、病状の重篤度を把握する指標の1つであるが、主観的な指標であるため、情報の共有がむずかしい。分光測色計による客観的な色の評価は、急性期の病態変化の評価に使用できる可能性を示すことができた。血圧やヘモグロビン濃度以外の因子も皮膚色の変化に関係することが示された。臨床現場に応用できるよう、様々な病態で皮膚色の測定を進めていくことが必要であると考える。