A new screening method for aortic stenosis by Doppler OCT

2023 Fiscal Year Final Research Report

• Project/Area Number: 19K18867
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 56060:Ophthalmology-related
• Research Institution: Asahikawa Medical College
• Principal Investigator: Song Youngseok 旭川医科大学, 医学部, 客員准教授 (00726341)
• Project Period (FY): 2019-04-01 – 2024-03-31
• Keywords: 網膜循環 / 網膜血流 / ドップラ / 光干渉断層計 / OCT

Outline of Final Research Achievements

Doppler Optical coherence tomography flow meter (DOCT flowmeter) measures several retinal blood flow parameters including retinal blood velocity and the amount of retinal blood flow). The retinal blood flow parameters provide retinal blood flow waveform (RBF waveform). Our studies have revealed that the RBF waveform reflects the conditions of arteriosclerosis both in the healthy subjects and the patients with hypertension, suggesting that the retinal blood flow measured by DOCT flowmeter can be used for screenings of several systemic diseases related to arteriosclerosis.

Free Research Field

網膜循環

Academic Significance and Societal Importance of the Research Achievements

DOCT flowmeterを用いた網膜血流測定が動脈硬化のスクリーニング検査として有用である可能性がある。本測定は簡便であり（測定時間３秒以内）、今後の更なる研究、臨床応用が期待される。