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2010 Fiscal Year Final Research Report

The effects of exercise on angiogenesis and oxidative stress in the brain after cerebral infarction

Research Project

  • PDF
Project/Area Number 20500474
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKawasaki Medical School

Principal Investigator

HIMI Naoyuki  Kawasaki Medical School, 医学部, 助教 (70412161)

Co-Investigator(Kenkyū-buntansha) HASHIMOTO Ken  川崎医科大学, 医学部, 助教 (80341080)
ENDO Kousuke  川崎医科大学, 医学部, 助教 (00350463)
Co-Investigator(Renkei-kenkyūsha) KOGA Tomoshige  川崎医療福祉大学, 医療技術学部, 教授 (50186649)
KUNIYASU Katsushi  川崎医療福祉大学, 医療技術学部, 准教授 (10299258)
Project Period (FY) 2008 – 2010
Keywords脳梗塞 / リハビリテーション / 酸化ストレス
Research Abstract

We tried to make diffuse small size infarction in the rat brain by microsphere injection and investigated early-stage effects of exercise in the present study.
After the injection of Microsphere, mild exercise(Excercise Group) for 7days or no exercise (No exercise Group) was loaded to the rats. There was no difference between groups on the expression of related proteins to angiogenesis and oxidative stress. However, cognitive function of exercise group was significantly recovered compared with no exercise group.

  • Research Products

    (4 results)

All 2011 2010 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results) Remarks (1 results)

  • [Journal Article] Changes in the Lactate Threshold During Treadmill Exercise After Microsphere-Induced Infarction in Rats2011

    • Author(s)
      Takahashi Hisashi, Himi Naoyuki, Katsushi Kuniyasu, Koga Tomoshige
    • Journal Title

      Journal of Stroke & Cerebrovascular Diseases (in press)

    • Peer Reviewed
  • [Presentation] 脳梗塞後の短期間運動が認知機能の回復に及ぼす効果2010

    • Author(s)
      氷見直之,高橋尚,古我知成,丸山恵美,国安勝司,宮本修
    • Organizer
      第65回日本体力医学会
    • Place of Presentation
      千葉
    • Year and Date
      2010-09-17
  • [Presentation] Early stage effects of exercise on cognitive dysfunction in cerebral infarction model rats by microsphere injection2010

    • Author(s)
      Himi Naoyuki, Takahashi Hisashi, Nakamura Emi, Kuniyasu Katsushi, Narita Kazuhiko, Koga Tomoshige, Miyamoto Osamu
    • Organizer
      第87回日本生理学会大会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-05-19
  • [Remarks] ホームページ等

    • URL

      http://www.kawasaki-m.ac.jp/med/study/info.php?id=209

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Published: 2012-01-26   Modified: 2016-04-21  

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