2010 Fiscal Year Final Research Report
Functional and structural analyses of novel hybrid type polyketide synthase Steely
| Project/Area Number |
20510196
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Living organism molecular science
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| Research Institution | Hokkaido University |
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Principal Investigator |
SAITO Tamao Hokkaido University, 理工学部, 准教授 (30281843)
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| Co-Investigator(Kenkyū-buntansha) |
MORITA Naoki (独)産業技術総合研究所, 生物プロセス研究部門分子生物工学研究グループ, 研究グループ長 (60371085)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 二次代謝産物 / ポリケタイド合成酵素 |
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| Research Abstract |
The soil microorganism, Dictyostelium, has novel hybrid-type polyketide synthase (PKS) known as 'Steely' ; Steely enzyme is formed by the fusion of type I and type III PKSs. In this study, we examined how these two different enzymes work together and what are the products of Steely enzymes. Finally, we examined the biological functions of these products.
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