2009 Fiscal Year Final Research Report

Regeneration study of olfactory bulb neurons using bone marrow stem cells

Research Project

Project/Area Number	20791196
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Otorhinolaryngology
Research Institution	Okayama University
Principal Investigator	YOSHINOBU Junko Okayama University, 医学部, 技術専門職員 (80448224)
Project Period (FY)	2008 – 2009
Keywords	再生医学 / 細胞・組織 / 脳・神経
Research Abstract	The regenerative therapy using bone marrow stem cells progressing remarkably in late years is expected as a new therapy for severe olfaction disorder that recovery is difficult by the current medical care. This study was conducted to examine the efficacy of the regenerative therapy using bone marrow cells in regeneration of olfactory bulb said to be more difficult than olfactory epithelium. As a result, it was found that the regenerative therapy using bone marrow cells had potential as a new therapy for not only the disorder of olfactory epithelium but also the disorder of olfactory bulb. Also, it was suggested that the use of cytokine raised efficacy of the regenerative therapy more.