2022 Fiscal Year Final Research Report
The relationship between the oligosaccharides in bovine colostrum and lactocrine function in dairy calves.
Project/Area Number |
20H03131
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Review Section |
Basic Section 42010:Animal production science-related
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Research Institution | Hiroshima University |
Principal Investigator |
Sugino Toshihisa 広島大学, 統合生命科学研究科(生), 教授 (90363035)
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Co-Investigator(Kenkyū-buntansha) |
櫛引 史郎 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門, 再雇用職員 (30355218)
朝隈 貞樹 国立研究開発法人農業・食品産業技術総合研究機構, 北海道農業研究センター, 上級研究員 (50374773)
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Project Period (FY) |
2020-04-01 – 2023-03-31
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Keywords | 乳用子牛 / 初乳 / 酸性オリゴ糖 |
Outline of Final Research Achievements |
In multiparous dairy cows, it demonstrated that the length of the dry period affects the concentration of acidic oligosaccharides. It also been revealed that there is a positive correlation between the concentration of acidic oligosaccharides and the body weight of newborn calves. Commercially colostrum replacer in Japan varied significantly in the concentration of acidic oligosaccharides due to differences in the manufacturing process. It was demonstrated that types of colostrum replacer that enhance IgG content through concentrated whey have lower concentrations of acidic oligosaccharides compared to colostrum derived from cows. Calves fed with colostrum replacer with high concentrations of acidic oligosaccharides exhibited good fecal score during the period of increased milk intake at 2-3 weeks of age. Therefore, it is speculated that providing colostrum replacer with high acidic oligosaccharide content until one month of age could enhance nutritional digestion in calves.
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Free Research Field |
家畜栄養生理学
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Academic Significance and Societal Importance of the Research Achievements |
初乳には,成長因子やインスリンなども豊富に含んでおり,これら因子が腸管機能の発達に影響する。乳用子牛の初乳に関する研究は多く,それらの成果は子牛の初乳管理に活用されており,FPTを中心にIgGを指標とした初乳給与基準の設定されており,また初乳に含まれる主要な成長因子,代謝ホルモン(インスリン等)と子牛の発育に関する知見は多い。しかし,依然として乳用子牛の下痢症,死廃率は高く,同様の飼養管理下でも個体により発育が異なるケースが多い。初乳に多く含まれる酸性オリゴ糖は腸管機能に影響することが知られており,本研究で得られた知見は酪農現場での乳用子牛の飼養管理の改善に寄与できる基礎的知見である。
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