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2022 Fiscal Year Final Research Report

Development of a new lung function imaging system using deep learning that adapts to the radiation therapy workflow.

Research Project

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Project/Area Number 20K16733
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 52040:Radiological sciences-related
Research InstitutionKyoto Prefectural University of Medicine

Principal Investigator

Kajikawa Tomohiro  京都府立医科大学, 医学(系)研究科(研究院), 助教 (30846522)

Project Period (FY) 2020-04-01 – 2023-03-31
Keywords肺機能画像 / 放射線治療 / 深層学習 / 画像処理 / CT画像
Outline of Final Research Achievements

We investigated the construction and accuracy verification of a deep learning system for generating lung function images based on CT images. Specifically, we constructed and adjusted a general deep learning image generation model and collected data that met the adaptation criteria. Then, we performed deep learning model training and accuracy evaluation on a total of 71 image data sets (lung function images, CT images) that were obtained. We preprocessed the data to enable smooth learning by the deep learning model. As a result, both qualitative and quantitative evaluations showed relatively good agreement. These results suggest that it is possible to generate lung function images from CT images using deep learning.

Free Research Field

放射線治療

Academic Significance and Societal Importance of the Research Achievements

放射線治療において,治療期間中に肺機能が変化することがあり,さらに肺機能を考慮することで有害事象の発生リスクを低減できることが知られている.そのため,肺機能を正確に考慮するためには治療回毎に肺機能画像を取得することが理想的である.一方,現行手法(SPECT ventilation/perfusion など)は他機による追加の撮像が必要であり,臨床ワークフローに導入することは現実的ではない.本研究の目的は,深層学習および画像処理を用い,治療回毎に取得される 3D CBCT画像のみに基づき肺換気画像を生成することである.本手法により,肺機能を考慮した適応放射線治療の足掛かりとなることを目指す.

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Published: 2024-01-30  

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