2012 Fiscal Year Final Research Report
Spacial regulation of cells during organogenesis
| Project/Area Number |
21247035
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Developmental biology
|
|---|
| Research Institution | Kyoto University (2011-2012)
Nara Institute of Science and Technology (2009-2010) |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SAITO Daisuke 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教 (90403360)
|
|---|
| Project Period (FY) |
2009 – 2012
|
| Keywords | 器官ネットワーク / 神経 / 血管 / 細胞挙動 / 空間配置 |
|---|
| Research Abstract |
During development, cell differentiation and tissue formation need to proceed at the right time and right space. The aim of this research is to understand how cells and tissues are correctly distributed in the developing embryo. We address such questions with a particular focus on neural crest cells, which undergo dynamic migration after emigrating from the neural tube. We found that neural crest cells intimately interact with non-neural crest cells, and also that complex molecular cascades are involved in such interactions. The cellular and molecular mechanisms revealed in this study are expected to be shared by other morphogenetic processes.
|
-
-
-
-
[Journal Article] Efficient genetic modification and germ-line transmission of pr imordial germ cells using piggyBac and Tol2 transposons.2012
Author(s)
Macdonald, J., Taylor, L., Sherman, A., Kawakami, K., Takahashi, Y., Sang, HM. and McGrew, MJ.
-
Journal Title
Proc. Natl. Acad. Sci. USA
Volume: 109
Pages: 1466-1472
DOI
Peer Reviewed
-
-
-
-
[Journal Article] Stable, conditional, and muscle-fiber-specific expression of electroporated transgenes in chick limb muscle cells.2011
Author(s)
Wang, H., Bonnet, A., Delfini, MC., Kawakami, K., Takahashi, Y. and Duprez, D.
-
Journal Title
Dev. Dyn
Volume: 240
Pages: 1223-1232
DOI
Peer Reviewed
-
[Journal Article] Conditional knockdown of target gene expression by tetracycline regulated transcription of double strand RNA.2011
Author(s)
Hou, X., Omi, M., Harada, H., Ishii, S., Takahashi, Y. and Nakamua, H.
-
Journal Title
Dev. Growth Differ
Volume: 53(1)
Pages: 69-75
DOI
Peer Reviewed
-
[Journal Article] Simultaneous expression of different transgenes in neurons and glia by combining in utero electroporation with Tol2 transposon mediated gene transfer system.2010
Author(s)
Yoshida, A., Yamaguchi, Y., Nonomura, K., Kawakami, K., Takahashi, Y. and Miura, M
-
Journal Title
Genes to Cells
Volume: 15(5)
Pages: 501-12
DOI
Peer Reviewed
-
-
-
[Journal Article] A combination of transposable elements and magnetic cell sorting provides a very efficient transgenesis system for chicken primary erythroid progenitors.2009
Author(s)
Mejia-Pous, C., Vinuelas, J., Faure, C., Koszela, J., Kawakami, K., Takahashi,Y. and Gandrillon, O.
-
Journal Title
BMC Biotechnology
Volume: 9
Pages: 81
DOI
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Remarks] (新聞掲載)個体発生過程における交感神経系の形成機構を解明 日刊工業新聞、京都新聞に掲載2012.6
-
-
[Remarks] (1)高橋淑子: 「動物の発生にみる遺伝子と細胞のドラマ」第2回出前授業, 2012,12,17 池田市
-
[Remarks] (2)高橋淑子:「卵の中をのぞいてみよう!体作りの不思議」第7回女子中高生のための関西科学塾 実験及び解説 京都大学2012,10,21, 京都市
-
[Remarks] (3)高橋淑子:「細胞の声をきく:動物の体作りと細胞のコミュニケーション」明石生涯学習指導者会後期研修会(明石市生涯学習センター), 2010,11,28, 明石市
-
[Remarks] (4)高橋淑子:「卵から体が出来上がる仕組み-細胞の社会-」学研都市6大学連携「市民公開講座」,2010,11,27, 京都市
-
[Remarks] (5)高橋淑子:放送大学特別講義「細胞の声を聞く」2012年より放映
