2011 Fiscal Year Final Research Report
Protection of infectious diseases of fish by co-cultured microbial product
| Project/Area Number |
21580378
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied veterinary science
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| Research Institution | Osaka Prefecture University |
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Principal Investigator |
KODAMA Hiroshi 大阪府立大学, 大学院・生命環境科学研究科, 教授 (20091449)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 穴あき病 / インネートイムニティー / 感染防御 / 共棲発酵微生物 / サイトカイン / 粘液胞子虫性やせ病 / Aeromonas salmonicida / Enteromyxum leei |
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| Research Abstract |
A microbial culture was prepared by co-cultivation of Lactobacillus paracasei, Saccharomyces cereviciae and Pichia membranifaciens. Oral administration of heat-inactivated co-cultured material to common carp or tiger puffer induced effective protection against infection with atypical Aeromonas salmonicida which causes ulcer disease, and myxosporean emaciation disease of tiger puffer caused by Enteromyxum leei, respectively. These results indicate that the co-cultured material, delivered in feeds, is effective in preventing infectious diseases through activation of innate immunity in fish.
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