2010 Fiscal Year Final Research Report
Visualization of the areas of glioblastoma invasion using a EGFR gene amplification as a marker of an individual tumor cell, and analysis of tissue reaction.
| Project/Area Number |
21700391
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | Gunma University |
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Principal Investigator |
MIYANAGA Tomomi Gunma University, 医学部, 助教 (30455951)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 膠芽腫 / 脳腫瘍 / 浸潤 / EGFR / 遺伝子増幅 / chromogenic in situ hybridization |
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| Research Abstract |
Glioblastoma is difficult to estimate the areas of tumor, because tumor cells infiltrate into the surrounding brain widely. In cases in which almost all tumor cells show amplification of the EGFR gene, CISH signals of amplification is available as a marker of isolated tumor cells. In the surrounding area of glioblastoma, it is difficult to identify the presence of tumor cells only by morphological information.
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