2023 Fiscal Year Final Research Report
Development of In vivo dosimetry technique for radiotherapy in consideration of liner energy transfer
| Project/Area Number |
21K15796
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 52040:Radiological sciences-related
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| Research Institution | Tokyo Metropolitan University (2022-2023)
National Institutes for Quantum Science and Technology (2021) |
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Principal Investigator |
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| Project Period (FY) |
2021-04-01 – 2024-03-31
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| Keywords | 放射線治療 / 重粒子線治療 / 放射線計測 |
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| Outline of Final Research Achievements |
The primary outcome of this research is the development of a technique that enables measurement within an approximate 1% margin of error for any radiation field, by evaluating the dependency of Linear Energy Transfer (LET) in spherical Si semiconductor detectors and calibrating in radiation fields with equivalent LET values.
Using this measurement method, the dose response to LET values ranging from 10.40 keV/um to 101.45 keV/um was assessed, demonstrating that the measurement error remains below 1% to a maximum of approximately 1.5%.
These findings represent a significant step towards overcoming the limitations of existing technologies, providing a crucial foundation for developing even more precise measurement methods through further research and experimentation.
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| Free Research Field |
医学物理
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| Academic Significance and Societal Importance of the Research Achievements |
現在、Liner energy transfer の高い放射線種を利用したMulti-ion beam therapyという放射線治療が活発に研究されている。この照射技術はC-ion beam単体の治療と比較して非常に高精度な照射が要求される。
高精度な照射に対しては、In-vivo dosimetry (IVD)という放射線治療中の患者体内の放射線量を測定することで、測定の正確さを監視しながら放射線治療を実施し、照射精度を担保する事が行われる。本研究の成果を利用することで、Multi-ion beam therapyでIVDを実施することができ、安全で安心な治療の実施に寄与する。
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