2012 Fiscal Year Final Research Report
Interaction between dental pulp stem cells and bone-marrow-derived cells during pulpal regeneration and its clinical implication
| Project/Area Number |
22390341
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Morphological basic dentistry
|
|---|
| Research Institution | Niigata University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
HONDA Masaki 日本大学, 歯学部, 准教授 (70361623)
HARADA Hidemitsu 岩手医科大学, 歯学部, 教授 (70271210)
IDA Hiroko 新潟大学, 医歯学系, 准教授 (60293213)
NAKATOMI Mitsushiro 新潟大学, 医歯学系, 助教 (10571771)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
WATANABE Nobukazu 東京大学, 医科学研究所, 特任准教授 (10334278)
MUTOH Noriko 神奈川歯科大学, 歯学部, 講師 (40510433)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 歯髄幹細胞 / 前駆細胞 / 象牙芽細胞 / 象牙質形成 / 象牙質・歯髄複合体 / 歯の再植 / 歯の移植 / 幹細胞ニッチ |
|---|
| Research Abstract |
Dental pulp stem cells retain proliferative activity and differentiation capacity for odontoblasts during pulpal healing following tooth injuries. Furthermore, donor-host interactions play a crucial role in the reorganization of dental pulp. We succeeded to establish the useful in vitro culture system for the evaluation of the dentin-pulp complex regeneration. These chronological changes in the pulp-dentin border in the in vitro organ culture were similar to the changes in the in vivo experimental models such as tooth replantation/transplantation.
|
Research Products
(47 results)
