2012 Fiscal Year Final Research Report
The development of method for liver fibrosis inhibition by controlling liver fibrosis
| Project/Area Number |
22590727
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Gastroenterology
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| Research Institution | Osaka City University (2012)
Kyoto University (2010-2011) |
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Principal Investigator |
MURAKAMI Yoshiki 大阪市立大学, 大学院・医学研究科, 病院講師 (00397556)
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| Project Period (FY) |
2010 – 2012
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| Keywords | マイクロ RNA / 肝線維化 / 肝発癌 |
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| Research Abstract |
Liver fibrosis in chronic liver disease was progressed without suitable medical treatment. We clarified the microRNA (miRNA) of which aberrant expression was related to the progression of liver fibrosis by using microarray analysis in liver
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[Journal Article] The expression level of miR-18b in hepatocellular carcinoma is associated with the grade of malignancy and prognosis BMC Cancer2013
Author(s)
Murakami Y, Tamori A, Itami S, Tanahashi T, Toyoda H, Tanaka M, Wu W, Brojigin N, Kaneoka Y, Maeda A,Kumada T, Kawada N, Kubo S and Kuroda M
Volume
13
Pages
99
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[Journal Article] Dysregulation of IFN system can lead to poor response to pegylated interferon and ribavirin therapy in chronic hepatitis C2011
Author(s)
Onomoto K, Morimoto S, Kawaguchi T, Toyoda H, Tanaka M, Kuroda M, Uno K, Kumada T, Matsuda F, Shimotohno K, Fujita T, and Murakami Y
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Journal Title
PLoS One
Volume: 6
Pages: e19799
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[Journal Article] Deregulation of miR-92a expression is implicated in hepatocellular carcinoma development2010
Author(s)
Shigoka M, Tsuchida A, Matsudo T, Nagakawa Y, Saito S, Suzuki Y, Aoki T, Murakami Y, Toyoda H, Kumada T, Bartenschlager R, Kato N, Ikeda M, Takashina T, Tanaka M, Suzuki R, Oikawa K, Takanashi M, Kuroda M
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Journal Title
Pathol Int
Volume: 60
Pages: 351-357
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