2012 Fiscal Year Final Research Report
Prediction of response to neoadjuvant chemotherapy in esophageal cancer patients
| Project/Area Number |
22591461
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | University of the Ryukyus |
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Principal Investigator |
SHIMOJI Hideaki 琉球大学, 大学院・医学研究科, 助教 (30305205)
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| Co-Investigator(Kenkyū-buntansha) |
NISHIMAKI Tadashi 琉球大学, 大学院・医学研究科, 教授 (70242427)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 食道外科学 |
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| Research Abstract |
The aim of this study was to evaluate the prediction of response to neoadjuvant chemotherapy in esophageal cancer patients. Eight patients were enrolled in this study. In these patients, Circulating Tumor Cells were not detected by Cell Search Method. And CEA m-RNA levels were not detected by RT -PCR. SCC m-RNA levels were detected in all patients, but we could not defined the relationship between the expression of SCC m-RNA and effectiveness of the neoadjuvant chemotherapy in esophageal cancer patients.
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