2012 Fiscal Year Final Research Report

Reevaluation of α-tricalcium phosphate foam which is not suitable for bone substitute material

Research Project

Project/Area Number	22592184
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Dental engineering/Regenerative dentistry
Research Institution	Yamaguchi University
Principal Investigator	UDOH Koh-ichi 山口大学, 大学院・理工学研究科, 准教授 (60145266)
Co-Investigator(Kenkyū-buntansha)	UEYAMA Yoshiya 山口大学, 大学院医学系研究科, 教授 (00168668)
Project Period (FY)	2010 – 2012
Keywords	α型リン酸三カルシウム / 骨補填材 / 足場材 / フォーム
Research Abstract	Fully interconnected -TCP foam was able to be fabricated using the polyurethane foam method, whereby polyurethane foam coated with -TCP slurry was sintered at 1,450 1,550°C and that no quenching was performed. The -TCP foam had extremely high porosity ranging between 90 and 95% and exhibited reasonable compressive strength ranging between 50 and 250 kPa. Based on these initial findings, it is highly recommended that in vivo evaluation be carried out to explore the possibility and suitability of -TCP foam as a bone substitute and/or scaffolding material for tissue engineering.

(4 results)