Multimodal neuroimaging studies of social cognition in schizophrenia

2014 Fiscal Year Final Research Report

• Project/Area Number: 23390290
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Psychiatric science
• Research Institution: Kyoto University
• Principal Investigator: MURAI Toshiya 京都大学, 医学(系)研究科(研究院), 教授 (30335286)
• Co-Investigator(Kenkyū-buntansha): FUJIWARA Hironobu 京都大学, 医学研究科, 特定病院助教 (10599608) ; HIRAO Kazuyuki 京都文教大学, 臨床心理学部, 准教授 (20512479) ; SAWAMOTO Nobukatsu 京都大学, 医学研究科, 講師 (90397547)
• Project Period (FY): 2011-04-01 – 2015-03-31
• Keywords: 神経心理学

Outline of Final Research Achievements

Impaired social cognition is considered a core contributor to unfavorable psychosocial functioning in schizophrenia. We investigated neural underpinnings of social cognitive impairment using high-resolution magnetic resonance imaging. As results, regarding major aspects of social cognition including empathy, Theory of Mind, and alexithymic tendency, we identified imaging correlates of them in specific cortical regions or in specific connectivities. In addition, we demonstrated that subjective quality of life is associated with pathology of brain regions relevant to social cognition.

Free Research Field

精神医学