2014 Fiscal Year Final Research Report
Construction of validation system for regenerative therapy by glycan profiling technology
Project/Area Number |
23791210
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Pediatrics
|
Research Institution | National Research Institute for Child Health and Development |
Principal Investigator |
INOUE Mayu 独立行政法人国立成育医療研究センター, 細胞医療研究部, 研究員 (40596920)
|
Project Period (FY) |
2011-04-28 – 2015-03-31
|
Keywords | 再生医療 / 幹細胞 / レクチン / 糖鎖プロファイリング |
Outline of Final Research Achievements |
The cell surface is covered with various glycoproteins, which play a crucial role in biological function. In this study, I aimed to define the status of somatic stem cells and pluripotent stem cells using glycan profiles. The glycan profiles promises to be of great value of stem cell validation for regenerative therapy, complementing more established methods such as gene expression analysis and epigenetic analysis.
|
Free Research Field |
幹細胞生物学
|