2016 Fiscal Year Final Research Report
The cell therapy and cell recruit using artificial dermis that can sustain the release od growth factors
| Project/Area Number |
24390399
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Plastic surgery
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| Research Institution | Kansai Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
鈴木 茂彦 京都大学, 医学(系)研究科(研究院), 教授 (30187728)
河合 勝也 京都大学, 医学(系)研究科(研究院), 准教授 (90273458)
益岡 弘 京都大学, 医学(系)研究科(研究院), 助教 (00600496)
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| Research Collaborator |
TAIRA Tsuguyoshi グンゼ株式会社, QOL研究所
INOIE Masukazu (株)ジャパンティッシュエンジニアリング
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| Project Period (FY) |
2012-04-01 – 2017-03-31
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| Keywords | 人工真皮 / 細胞成長因子 / 徐放 |
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| Outline of Final Research Achievements |
We have developed a novel artificial dermis, collagen/gelatin sponge (CGS), which is capable of sustained release of basic fibroblast growth factor (bFGF) for more than 10 days.CGS impregnated with bFGF accelerate capillary formation and promote wound healing process of chronic skin ulcers such as diabetic ulcers of pressure ulcers.In this study, we showed that CGS could sustain the release of PRP (Platelet rich plasma). In addition, CGS could be used for the scaffold for adipose tissue formation in combination with adipose tissue derived stem cells.
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| Free Research Field |
形成外科学
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