Regulation of bone remodeling surrounding implant by low-content hydrogen DLC

2014 Fiscal Year Final Research Report

• Project/Area Number: 24390434
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Prosthetic dentistry
• Research Institution: Hiroshima University
• Principal Investigator: NIKAWA Hiroki 広島大学, 医歯薬保健学研究院, 教授 (10228140)
• Co-Investigator(Kenkyū-buntansha): TAJI Tsuyoshi 広島大学, 大学院医歯薬保健学研究(歯), 准教授 (80284214)
• Co-Investigator(Renkei-kenkyūsha): NAKATANI Tatsuyuki 岡山理科大学, 技術科学研究所, 教授 (50520920) ; KEISHI Okamoto トーヨーエイテック株式会社, 表面処理事業部企画開発課, 課長 (90507724) ; MAKIHIRA Seicho 九州大学, 大学院歯学研究院, 准教授 (80304450) ; MINE Yuichi 広島大学, 大学院医歯薬保健学研究院, 特任助教 (60605989)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: DLC / インプラント / 骨リモデリング / 破骨細胞 / 骨芽細胞

Outline of Final Research Achievements

It is necessary to develop the novel fixture considering the strong osseointegration and bone remodeling for success of dental implant treatment. We investigated the effects of DLC-treated Ti disks (DLC-Ti) including low amount of hydrogen on osteoblast and osteoclast differentiation in vitro.
This study suggests that specific-hydrogen content of DLC-Ti can affect response of osteoblast and osteoclast cells. In future, specific-hydrogen content of DLC-Ti may be useful for the material of dental implants that gives good prognosis.

Free Research Field

歯学