Vascular endothelial dysfunction and hypertension in general population

2014 Fiscal Year Final Research Report

• Project/Area Number: 24590790
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Osaka University
• Principal Investigator: CUI Renzhe 大阪大学, 医学(系)研究科(研究院), 助教 (40375514)
• Co-Investigator(Kenkyū-buntansha): ISO Hiroyasu 大阪大学, 医学系研究科, 教授 (50223053) ; KIYAMA Masahiko 大阪がん循環器病予防センター, 予防推進部, 部長 (10450925) ; OHIRA Tetsuya 福島県立医科大学, 医学部, 教授 (50448031)
• Co-Investigator(Renkei-kenkyūsha): KITAMURA Akihiko 大阪大学, 医学系研究科, 準教授 (80450922)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: FMD検査 / ｃGMP / 高血圧 / 血管内皮機能 / 疫学研究

Outline of Final Research Achievements

This study investigated the association of flow mediated dilatation (FMD) with brachial blood pressure and central aortic pressure in general population. FMD values was inversely associated with systolic and diastolic blood pressure, central aortic pressure, and heavy drinking. Also, central aortic pressure was positively associated with ECG ST-T abnormalities and left ventricular hypertrophy independent of brachial blood pressure.

Free Research Field

循環器疾患の疫学