2014 Fiscal Year Final Research Report
Basic research of SIRT1 for treatment of allergic rhinitis
| Project/Area Number |
24592574
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
|
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| Research Institution | Hokkaido University |
|---|
Principal Investigator |
NAKAMARU Yuji 北海道大学, 大学病院, 講師 (20344509)
|
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | アレルギー性鼻炎 / SIRT1 / IL-33 |
|---|
| Outline of Final Research Achievements |
In this study, we compared IL-33 expression at the inferior turbinate of the control and patients with allergic rhinisitis. IL-33 expression of the allergic rhinitis patients were up-regulated than those of the control. We next compared SIRT1 expressions of the inferior tubinates between the control and allergic rhinitis patients. The SIRT1 expressions of the allergic patients significantly lower than those of the controls.
|
| Free Research Field |
耳鼻咽喉科
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