Establishment of radiological evaluation method for the regenerated bone

2014 Fiscal Year Final Research Report

• Project/Area Number: 24593063
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Surgical dentistry
• Research Institution: Nihon University
• Principal Investigator: YONEHARA Yoshiyuki 日本大学, 歯学部, 教授 (00251299)
• Co-Investigator(Kenkyū-buntansha): TSUTSUMI Sadami 金沢工業大学, 先端電子技術応用研究所, 客員教授 (00028739) ; HONDA Kazuya 日本大学, 歯学部, 教授 (30199567) ; NAMAKI Shunsuke 日本大学, 歯学部, 助教 (70386077) ; OOKI Hiderou 日本大学, 歯学部, 教授 (80147628) ; UEHARA Hiroyuki 日本大学, 歯学部, 非常勤医員 (90409102)
• Research Collaborator: MASHIMO Takayuki ; IWATA Jun ; URYU Takeshi
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 骨再生 / 骨造成 / 人工骨 / 画像評価

Outline of Final Research Achievements

The observation of the bone regenerative process from periosteum suggest that the periosteum has osteogenic capacity and the peak of bone regeneration from the periosteum occurs around 4 to 6 weeks. The evaluation of the usefulness of regenerative bone from periosteum as a new graft material for the repair of bone defects indicate that the regenerative bone from periosteum is a useful reconstructive material. The results of tetrapod-shaped granular artificial bone(TB) implantation suggest that TB presented good shape stability and mechanical strength. TB might be useful for bone augmentation of flat bone area as compared with other currently used artificial graft materials and autogenous bone. The results of bone defect repair study showed higher volumes of the newly formed bones in the TB and collagen implantation group than in the TB group or control group. The combinatorial use of TB and collagen would be an effective strategy for the treatment of bone defect.

Free Research Field

口腔外科，顎顔面再建外科，形成外科，再生医療