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2013 Fiscal Year Final Research Report

Enhancement of functional expression of osteoblastic and periosteal cells by gingival fibroblasts with paracrine effect of fibroblastic growth factors

Research Project

  • PDF
Project/Area Number 24792114
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Prosthetic dentistry
Research InstitutionTokyo Dental College

Principal Investigator

YAMADA Masahiro  東京歯科大学, 歯学部, 講師 (90549982)

Project Period (FY) 2012-04-01 – 2014-03-31
Keywords骨再生 / 線維芽細胞増殖因子 / 歯肉結合組織 / 細胞間相互作用
Research Abstract

Gingival fibroblasts enhanced osteoblastic and periosteal proliferation and differentiation. The mechanism was involved in paracrine secretion of FGF-1 and -18 from GF and subsequent autocrine secresion of these growth factors from osteoblasts and periosteal cells.

  • Research Products

    (16 results)

All 2013 2012 Other 0

All Journal Article (8 results) Presentation (4 results) Remarks (4 results)

  • [Journal Article] Early-stage osseointegration capability of a submicrofeatured titanium surface created by microroughening and anodic oxidation2013

    • Author(s)
      Yamada M, Ueno T, Minamikawa H, Ikeda T, Nakagawa K, Ogawa T
    • Journal Title

      Clin Oral Implants Res

      Volume: 24(9) Pages: 991-1001

  • [Journal Article] Success rate, healing time, and implant stability development of photofunctionalized dental implants2013

    • Author(s)
      Funato A, Yamada M, Ogawa T
    • Journal Title

      Int J Oral Maxillofac Implants

      Volume: 28(5) Pages: 1261-71

  • [Journal Article] N-acetyl cysteine as an osteogenesis-enhancing molecule for bone regeneration2013

    • Author(s)
      Yamada M, Tsukimura N, Ikeda T, Sugita Y, Att W, Kojima N, Kubo K, Ueno T, Sakurai K, Ogawa T
    • Journal Title

      Biomaterials

      Volume: 34(26) Pages: 6147-56

  • [Journal Article] A novel combined surgical approach to vertical alveolar ridge augmentation with titanium mesh, resorbable membrane, and rhPDGF-BB : a retrospective consecutive case series2013

    • Author(s)
      Funato A, Ishikawa T, Kitajima H, Yamada M, Moroi H
    • Journal Title

      Int J Periodontics Restorative Dent

      Volume: 33(4) Pages: 159-66

  • [Journal Article] Activation of osteoblastic differentiation through calcium supplement by beta-tricalcium phosphate collagen composite leading to initial inner bone formation2013

    • Author(s)
      加藤英治, 山田将博, 櫻井 薫
    • Journal Title

      日本口腔インプラント学会誌

      Volume: 26(3) Pages: 405-424

  • [Journal Article] Anti-oxidant amino acid derivative as a multifunctional molecule for bone regeneration2013

    • Author(s)
      山田将博, 小川隆広, 櫻井 薫
    • Journal Title

      日本補綴歯科学会誌

      Volume: 5(4) Pages: 411-413

  • [Journal Article] Bone integration capability of nanopolymorphic crystalline hydroxyapatite coated on titanium implants2012

    • Author(s)
      Yamada M, Ueno T, Tsukimura N, Ikeda T, Nakagawa K, Hori N, Suzuki T, Ogawa T
    • Journal Title

      Int J Nanomedicine

      Volume: 7 Pages: 859-73

  • [Journal Article] N-acetyl Cysteine Improves Affinity of Beta-Tricalcium Phosphate Granules for Cultured Osteoblast-like Cells2012

    • Author(s)
      Yamada, M., Minamikawa, H., Ueno, T., Sakurai, K., Ogawa, T
    • Journal Title

      J Biomater Appl

      Volume: 27(1) Pages: 37-36

  • [Presentation] Establishment of connective tissue integration with alkali-heat treated titanium surface2013

    • Author(s)
      Kato, E., Yamada, M. and Sakurai K
    • Organizer
      29th Annual Meeting of Academy of Osseointegration
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2013-03-06
  • [Presentation] Cytofunctional preconditioning for auto-cell transplantation to enhance bone regeneration using antioxidant amino acid derivative2012

    • Author(s)
      Yamada, M., Ogawa, T. and Sakurai K
    • Organizer
      29th Anniversary Meeting of Academy of Osseointegration
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2012-03-06
  • [Presentation] N-acetyl Cysteine Alleviates Damage of Epithelial Monolayer from PMMA Extracts0

    • Author(s)
      Nishimiya H, Yamada M, Ueda T and Sakurai K
    • Organizer
      the 90th General Session and Exhibition of the IADR
    • Place of Presentation
      Seattle, USA
    • Year and Date
      00000322
  • [Presentation] Alkali-heat-treated Titanium Surface Enhances Fibroblastic Collagen Deposition and Binding Strength0

    • Author(s)
      Yamada M, Kato E and Sakurai K
    • Organizer
      the 90th General Session and Exhibition of the IADR
    • Place of Presentation
      Seattle, USA
    • Year and Date
      00000320
  • [Remarks] 東京歯科大学HRC プロジェクト研究HRC 第8プロジェクト・免疫機能・トランスレーショナル研究グループホームページ

    • URL

      http://www.tdc.ac.jp/dept/osc/hrc8/hrc8g2ac.html

  • [Remarks] 東京歯科大学有床義歯補綴学講座ホームページ

    • URL

      http://www.tdc.ac.jp/dept/rpg/

  • [Remarks] LinkedIn

    • URL

      https://www.linkedin.com/profile/view?id=243436736&trk=nav_responsive_tab_profile_pic

  • [Remarks] Research gate

    • URL

      https://www.researchgate.net/profile/Masahiro_Yamada?ev=hdr_xprf

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Published: 2015-06-25   Modified: 2015-08-12  

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