2016 Fiscal Year Final Research Report
Effects of spices on the digestive muscle activities under stress loadings
Project/Area Number |
25350146
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Eating habits
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Research Institution | Japan Women's University |
Principal Investigator |
KIMOTO Mari 日本女子大学, 家政学部, 教授 (60101565)
|
Project Period (FY) |
2013-04-01 – 2017-03-31
|
Keywords | 香辛料 / ストレス / 重力負荷 / 回腸 / 大腸 / 平滑筋運動 / 性差 / ラット |
Outline of Final Research Achievements |
The purpose of this study was to clarify the spice-induced effects on the digestive movements during stress loadings.In stress loading (3G), topical application of Capsaicin enhanced amplitudes of ileum contraction at 30 day and those of colon contraction at 1 day, but, decreased at 30 day in male rats. By contrast, there were no significant changes in amplitudes of digestive activities in female rats, suggesting sex differences were clear. Effects of oral intake of Chili on the digestive muscle activities were stronger in male than in female rats. Oral intake of Sansho, Ginger or Wasabi was partly effective on the digestive activities in both ileum and colon under stress free and stress loaded condition. These effects were also sex-related, however, a fixed pattern was not observed in the modulation of smooth muscle activities induced by each spice. Acetylcholine-induced contraction or adrenalin-induced inhibition of muscle activities were modulated by spices under stress condition.
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Free Research Field |
摂食生理学 行動生理学 神経生理学
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