Preparation of the guideline for biomarkers-based personlized treatment for patients with advanced lung cancer

2015 Fiscal Year Final Research Report

• Project/Area Number: 25462179
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Respiratory surgery
• Research Institution: Kagawa University
• Principal Investigator: Liu Dage 香川大学, 医学部, 助教 (30314941)
• Co-Investigator(Kenkyū-buntansha): Nakano Jun 香川大学, 医学部, 助教 (80437673) ; Tokunaga Masayosi 香川大学, 医学部付属病院, 助教 (20635825) ; Yokomise Hiroyasu 香川大学, 医学部, 教授 (80231728) ; Ueno Masaki 香川大学, 医学部, 教授 (30322267)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: バイオマーカー / 進行期肺癌 / 個別化治療 / 化学療法 / 抗癌剤耐性 / ガイドライン作成

Outline of Final Research Achievements

Tailor-made medicine is important for improving the result of cancer treatment. Cancer related biomarkers were comprehensively analysied and biomarkers-based chemotherapy were used into the clinical management in our institude. We tried to establish a simple and standardized [biomarkers-bassed ailor-made medicine selectting system] for widespreading the benefit of biomarkers. The in vitro 3D drug sensitivity test (CD-DST method) and prespective study were performed to verification of the value of biomarkers. These results of our study have been adopted by domestic and international conferences, and the usefness of biomarkers-bassed ailor-made medicine for patients with advanced-stage lung cancer was appealled abroad.

Free Research Field

医歯薬学