2014 Fiscal Year Final Research Report
Regulation of chromatin structure and gene expression in cross-tolerance to environmental stress
| Project/Area Number |
25840007
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Molecular biology
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | ストレス応答 / シグナル伝達 / 遺伝子発現制御 / クロマチン |
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| Outline of Final Research Achievements |
We have studied cellular responses to low-dose environmental stress. Cross-tolerance is an adaptive phenomenon, in which exposure to low-dose stress confers transient resistance to other form of high-dose stress. Previously we have identified Cpc2 as an important factor for cross-tolerance. This study revealed that Cpc2 plays a role in the regulation of stress-induced gene expression via facilitating nucleosome remodeling.
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| Free Research Field |
分子生物学
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