2016 Fiscal Year Final Research Report
Development of clinical application method of cancer / stem cell related molecule in head and neck cancer
Project/Area Number |
26460463
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Human pathology
|
Research Institution | National Cancer Center Japan |
Principal Investigator |
Mori Taisuke 国立研究開発法人国立がん研究センター, 中央病院, 医員 (00296708)
|
Research Collaborator |
Yoshimoto Seiichi
Itami Jun
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Keywords | 頭頸部癌 / 扁平上皮癌 / 幹細胞関連分子 |
Outline of Final Research Achievements |
Head - and - neck squamous cell carcinoma, which overexpresses EpCAM, a stem cell - related molecule, was found to be radioresistant. These can be said to be research results directly linked to clinical practice. The expression of EpCAM was thought to make clinical application possible by using microscopic biopsy specimens usually used for diagnosis of cancer and easy to judge by immunohistological examination.
|
Free Research Field |
人体病理
|