Clarification of the metastatic cascade mediated through the microRNA in bone marrow from gastric cancer cases.
| Project/Area Number |
21791297
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Digestive surgery
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| Research Institution | Kyushu University |
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Principal Investigator |
ISHIMARU Shinya Kyushu University, 大学病院, 医員 (10529887)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 胃癌 / microRNA / 骨髄 / マイクロアレイ / 転 / 転移 / ゲノム |
|---|
| Research Abstract |
MicroRNA array and gene expression array were performed with bone marrow of gastric cancer patient with/without metastases (n=4, respectively). Hsa-mir-144 was up-regulated in metastasis positive cases, and fosb, target of has-mir-144 was downregulated. Fosb depression showed clinicopathological significance (N, P etc).
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Report
(3 results)
Research Products
(26 results)
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[Presentation] The Clinicopathological Significance of Genomic Aberrations of MicroRNA Locus in Colorectal Cancer Patients.2010
Author(s)
S.Ishimaru,K.Mimori,K.Shibata,T.Sudo,T.Yokobori,N.Nishida,S.Akiyoshi,R.Kogo,T.Sato,H.Toh,K.Sugihara,M.Mori.
Organizer
63th The Surgical Society of Oncology.
Place of Presentation
St.Louis,MO
Year and Date
2010-03-06
Related Report
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[Presentation] clinical significance of miR-125 expression in colorectal cancer patients.2010
Author(s)
T.Yokobori,K.Mimori,F.Tanaka,K.Shibata, T.Sudo,S.Ishimaru,S.Akiyoshi,N.Nishi da,R.Kogo,H.Kuwano,M.Mori.
Organizer
63th The Surgical Society of Oncology.
Place of Presentation
St.Louis,MO
Year and Date
2010-03-06
Related Report
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