2015 Fiscal Year Final Research Report
Analyses of behavior incompatibility triggered by expression changes of pigmentation genes
Project Area | Correlative gene system: establishing next-generation genetics |
Project/Area Number |
23113008
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Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
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Allocation Type | Single-year Grants |
Review Section |
Biological Sciences
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Research Institution | Tokyo Metropolitan University (2012-2015) National Institute of Genetics (2011) |
Principal Investigator |
Takahashi Aya 首都大学東京, 理工学研究科, 准教授 (90370121)
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Co-Investigator(Kenkyū-buntansha) |
OSADA Naoki 北海道大学, 情報科学研究科, 准教授 (70416270)
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Project Period (FY) |
2011-04-01 – 2016-03-31
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Keywords | 体色変異 / 性行動 / ドーパミン代謝系 / 多面発現 / ショウジョウバエ / 種分化 / シス遺伝子発現制御 / トランス遺伝子発現制御 |
Outline of Final Research Achievements |
This study focused on dopamine biosynthesis pathway genes, which has a pleiotropic effect on both body pigmentation and behavior, as genes potentially involved in reproductive isolation triggered by environmental adaptation. We found unexpectedly complex cis-regulatory polymorphisms in these genes and a genetic variant that is likely to change both pigmentation and behavior. From a wider viewpoint of the “Correlative gene systems”, another contribution of this study was to elucidate various associations between cis/trans-regulatory variations and genomic factors by conducting a novel type of genome-wide transcriptome analysis.
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Free Research Field |
進化遺伝学
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