Establishment of peri-implantitis treatment based on radical disinfection technique

2017 Fiscal Year Final Research Report

• Project/Area Number: 15H05033
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Tohoku University
• Principal Investigator: Sasaki Keiichi 東北大学, 歯学研究科, 教授 (30178644)
• Co-Investigator(Kenkyū-buntansha): 庭野 吉己 東北大学, 歯学研究科, 教授 (40375184) ; 菅野 太郎 東北大学, 歯学研究科, 教授 (30302160) ; 中村 圭祐 東北大学, 歯学研究科, 講師 (30431589) ; 天雲 太一 東北大学, 歯学研究科, 助教 (80451425)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 水酸化ラジカル / インプラント周囲炎 / ラジカル殺菌

Outline of Final Research Achievements

In this project, in vitro and in vivo tests were performed with an aim of application of radical disinfection technique to treatment for peri-implantitis. In vivo test, where peri-implantitis caused around implants installed in dogs were treated with radical disinfection technique. However, there was no significant difference between the test and control groups. Thus, to find more suitable treatment conditions, in vitro test was additionally performed. The results demonstrated that the radical disinfection technique could recondition the titanium surface that had been previously contaminated by bacteria for subsequent osteoblastic cells. Therefore, future study should focus more on the establishment of treatment condition that enables to acquire re-osseointegration around the implants suffering from peri-implantitis.

Free Research Field

歯科補綴学