The improvement effect of periodontal disease by cacao bean extract

2016 Fiscal Year Final Research Report

• Project/Area Number: 15H06697
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Epidemiology and preventive medicine
• Research Institution: Kanagawa Dental College
• Principal Investigator: Sasaki Haruka 神奈川歯科大学, 大学院歯学研究科, 特別研究員 (50757200)
• Project Period (FY): 2015-08-28 – 2017-03-31
• Keywords: カカオ抽出物

Outline of Final Research Achievements

It is reported that cocoa bean extract has the inhibition effects of the collagenase produced by Porphyromonas gingivalis (P. gingivalis) such as the periodontal pathogenic bacteria. Therefore, we assessed the improvement effect of periodontal disease using cocoa bean extract (CBP and PW-VE-R) against P. gingivalis. The antimicrobial activity of cocoa bean against P. gingivalis and biofilm was recognized by using CBP and PW-VE-R. In addition, the scavenging activities against the reactive oxygen species such superoxide and hydroxyl radical wer indicated with cocoa bean extract. These results suggested that cocoa bean extract might have the improvement effect on periodontal tissue destruction.

Free Research Field

微生物