2010 Fiscal Year Final Research Report
New indications and possibility for other brain malignancies for BNCT using positron emission tomography
| Project/Area Number |
21890283
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Osaka Medical College |
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Principal Investigator |
MIYATA Shirou Osaka Medical College, 医学部, 非常勤医師 (30550230)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 脳腫瘍 / PET / アミノ酸 / LAT-1 / 中性子捕捉療法 / BPA / 転移性脳腫瘍 / 画像診断 |
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| Research Abstract |
In our basic experiment, accumulation of F-BPA and BPA had some differences. By the case which accumulation of F-BPAPET was high in, the LAT-1 staining showed strong positive depending on accumulation by the PET. Only blood vessel was strong positive by some cases, and it was thought that the adaptation to BNCT should be careful. Also, we think about BPA-PET with an essential examination when accumulation of F-BPAPET remains for many metastatic brain tumors moderately and decides by indication of BNCT using BPA for a metastatic brain tumor.
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