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Optimization of influenza vaccination policy with consideration of Japanese social structure

Research Project

Project/Area Number 18K17369
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
Research InstitutionNational Center for Global Health and Medicine

Principal Investigator

Tsuzuki Shinya  国立研究開発法人国立国際医療研究センター, 国際感染症センター, 応用疫学研究室医長 (60634912)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2018: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsインフルエンザ / COVID-19 / 予防接種 / 費用対効果分析 / 疾病負荷 / 数理モデル / 接触行列 / インフルエンザ様疾患 / 予防接種政策 / 感染症疫学
Outline of Final Research Achievements

The disease burden of influenza considering Japan's unique healthcare system was analyzed and the results were published as two original articles (DOI:10.1186/s12889-019-6600-0, DOI:10.1186/s12889-020-08603-x). The results integrated in the second year were published in as an original article (DOI:10.1016/j.vaccine.2019.11.001), suggesting that influenza vaccination was more cost-effective in Japan if children were prioritized.
The plan of the research project was changed after the COVID-19 pandemic to examine differences in the burden of disease caused by COVID-19 and influenza (DOI:10.1017/S0950268821002569).

Academic Significance and Societal Importance of the Research Achievements

当初の研究計画の元、我が国における季節性インフルエンザの予防接種政策は高齢者よりも小児を優先対象とした方が費用対効果に優れる可能性が示唆された。これは現実の予防接種政策とは異なるものであり、今後予防接種政策の再検討において有益な知見と考えられる。
COVID-19の流行により我々の社会は一変し研究計画も変更を余儀なくされた。変更後の研究計画に従い季節性インフルエンザ・COVID-19それぞれのもたらす疾病負荷を明らかにし、COVID-19が現状の社会における重要課題であることが定量的に明らかになった。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (12 results)

All 2022 2021 2020 2019 2018 Other

All Int'l Joint Research (4 results) Journal Article (5 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 4 results,  Open Access: 4 results) Presentation (3 results) (of which Int'l Joint Research: 2 results)

  • [Int'l Joint Research] University of Antwerp(ベルギー)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] National Cancer Center Korea/Seoul National University(韓国)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] Public Health England/LSHTM(英国)

    • Related Report
      2019 Research-status Report
  • [Int'l Joint Research] Public Health England(英国)

    • Related Report
      2018 Research-status Report
  • [Journal Article] The burden of isolation to the individual: a comparison between isolation for COVID-19 and for other influenza-like illnesses in Japan2021

    • Author(s)
      Tsuzuki Shinya、Ohmagari Norio、Beutels Philippe
    • Journal Title

      Epidemiology and Infection

      Volume: 150 Pages: 1-7

    • DOI

      10.1017/s0950268821002569

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] COVID-19 Vaccine Prioritisation in Japan and South Korea2021

    • Author(s)
      Chun June Young、Jeong Hwichang、Beutels Philippe、Ohmagari Norio、Kim Yongdai、Tsuzuki Shinya
    • Journal Title

      medRxiv

      Volume: NA

    • DOI

      10.1101/2021.04.16.21255649

    • Related Report
      2021 Annual Research Report
    • Open Access / Int'l Joint Research
  • [Journal Article] Modelling the optimal target age group for seasonal influenza vaccination in Japan2020

    • Author(s)
      Tsuzuki Shinya、Baguelin Marc、Pebody Richard、van Leeuwen Edwin
    • Journal Title

      Vaccine

      Volume: 38 Issue: 4 Pages: 752-762

    • DOI

      10.1016/j.vaccine.2019.11.001

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The Characteristics of Influenza-Like Illness Management in Japan2020

    • Author(s)
      Tsuzuki Shinya, Yoshihara Keisuke
    • Journal Title

      BMC Public Health

      Volume: -

    • NAID

      120006988207

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Economic consequences of Japanese schools’ recovery certificate policy for seasonal influenza2019

    • Author(s)
      Shinya Tsuzuki
    • Journal Title

      BMC Public Health

      Volume: 1 Issue: 1 Pages: 1-7

    • DOI

      10.1186/s12889-019-6600-0

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 隔離による個人への負荷:COVID-19と他のインフルエンザ様疾患の比較2022

    • Author(s)
      都築慎也
    • Organizer
      第32回日本疫学会学術総会
    • Related Report
      2021 Annual Research Report
  • [Presentation] The Characteristics of Influenza-Like Illness Management in Japan2019

    • Author(s)
      Tsuzuki Shinya
    • Organizer
      IDWeek2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Cost-effectiveness Analysis of Seasonal Influenza Vaccination in Japan2018

    • Author(s)
      Shinya Tsuzuki, Marc Baguelin, Richard Pebody, and Edwin van Leeuwen
    • Organizer
      IMED 2018
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research

URL: 

Published: 2018-04-23   Modified: 2023-01-30  

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