| Project/Area Number |
22590557
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Hygiene
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| Research Institution | Kanazawa Medical University |
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Principal Investigator |
MORIKAWA Yuko 金沢医科大学, 看護学部, 教授 (20210156)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAGAWA Hideaki 金沢医科大学, 医学部, 教授 (00097437)
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| Co-Investigator(Renkei-kenkyūsha) |
NISHIJO Muneko 金沢医科大学, 医学部, 准教授 (40198461)
SAKURAI Masaru 金沢医科大学, 医学部, 准教授 (90397216)
NAKAMURA Koshi 金沢医科大, 学医学部, 准教授 (80422898)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 産業衛生 / 夜勤交代勤務 / がん / 前立腺がん / PSA / 8OHデオキシグアノシン / 交代勤務 / 深夜勤務 / ハイドロキシデオキシグアノシン / 前立腺疾患 / 罹患 |
|---|
| Research Abstract |
We investigated the effects of night and shift work on cancer risk using serum prostatic specific antigen(PSA) and urinary 8-hydroxydeoxyguanosine (8-OHdG) as markers of cancer risk. However, we could not get the positive relationship between night and shift work and cancer risk. The study population consisted of 702 male employees aged 50-66 years in a factory in Japan. PSA level rose with increasing age, but not related with occupational factors including work schedule. The urinary8-OHdG level was the highest among the subjects engaged shift work without midnight shift, but statistically not significant.
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