Research Project
Grant-in-Aid for Scientific Research on Priority Areas
Human cells possess five RecQ family helicases, RECQL1, BLM, WRN, RTS, and RECQL5, whose defects cause a predisposition to cancer. In this study, functions of these RecQ family helicases were investigated and following results were obtained. BLM functions at the last stage of DNA replication, segregation of replicated DNA and sister chromatid cohesion. RTS is involved in DNA replication and repair of DNA double strand breaks. Finally, RECQL1 and RECQL5 are involved in early stages of recombination.
All 2010 2009 2008 2007 2006 2005
All Journal Article (87 results) (of which Peer Reviewed: 68 results) Presentation (29 results) Book (5 results)
Mol. Cell. Biol 30
Pages: 2460-2472
Nuc.Acids Res. (in press)
Mol.Cell.Biol. (in press)
Genes Cells 14
Pages: 1271-1330
Protein Sci 18
Pages: 2252-2264
FEBS J 276
Pages: 3382-3391
DNA Repair 8
Pages: 690-696
Biochem. Biophys. Res. Commun 379
Pages: 233-238
Mol. Bio. Cell 20
Pages: 937-947
Protein Sci. 18
FEBS Journal 276
Genes Genet.System 84
Pages: 171-178
Biochem.Biophys.Res.Commun. 379
Mol.Biol.Cell 20
Mol. Biol. Cell 20
DNA Repair (in press)
Genes Genet. Syst 83
Pages: 427-431
Gene Dev 22
Pages: 2843-2855
Cell Signal 20
Pages: 1978-1985
Biochem. Biophys. Res. Commun 372
Pages: 126-130
DNA Repair 7
Pages: 879-889
Biochim. Biophys. Acta 1782
Pages: 75-8
Pages: 75-81
Genes Dev 22
Genes Genet. System 83
DNA Repair (In press)
Genes Genet. Syst. 83
Pages: 95-100
J. Cell Biol 179
Pages: 53-63
Nuc. Acids Res 35
Pages: 4989-5000
EMBO Reports 8
Pages: 685-690
Biochem. Biophys. Res. Commun 356
Pages: 1031-1037
Cell Cycle 6
Pages: 1090-1095
Pages: 3109-3117
Biochem. Biophys. Res. Commun 355
Pages: 835-841
Mut. Res 617
Pages: 90-97
Genes Genet. Syst 82
Pages: 157-160
10024394124
Biochim. Biophys. Acta 1773
Pages: 556-564
Biophys. Res. Commun 354
Pages: 222-226
Pages: 353-362
J. Cell Biol. 179
Nucleic Acids Res. 35
EMBO Rep. 8
Biochem. Biophys. Res. Commun. 356
Biochem. Biophys. Res. Commun. 355
Genes Genet. Syst. 82
Biochem. Biophys. Res. Commun. 354
Nucleic Acids Res. 35・2
Biochem. Biophys. Res. Commun. 354・1
Biochim. Biophys. Acta 1773・4
Biochem. Biophys. Res. Commun. 355・3
Nucleic Acids Res. (in press)
Cell Cycle (in press)
Biochem. Biophys. Res. Commun 351
Pages: 935-939
DNA Repair 5
Pages: 1459-1474
Pages: 1307-1316
Cell 127
Pages: 509-522
Res. Commun 348
Pages: 62-69
Mutat. Res 600
Pages: 177-183
Mol. Cell. Biol 26
Pages: 6299-6307
Nuc. Acids Res 34
Pages: 3389-3398
Cell 127・3
Mol. Cell. Biol. 26・16
DNA Repair 5・7
Pages: 816-828
Nucleic Acids Res. 34・11
Biochem. Biophys. Res. Commun. 348・1
DNA Repair 5・11
DNA Repair 5・12
Biochem. Biophys. Res. Commun. 351・4
J. Biol. Chem 280
Pages: 19689-19694
EMBO J 24
Pages: 418-427
Genes Cells 10
Pages: 13-22
DNA Repair 4
Pages: 191-201
EMBO Journal 24
Nucleic Acids Research 33
Pages: 765-775
J.Biol.Chem. 280
Genes to Cells 10
Pages: 12-22